Ketamine for depression

Ketamine Treatment for Depression in Los Angeles

Utilizing ketamine for depression is a breakthrough therapy that is uniquely effective in treating depression when used in a clinical setting. Ketamine infusions often work better and faster than traditional treatment methods, including prescription antidepressants.

Antidepressant medications can take weeks or even months to reach therapeutic levels in your system. Even then, most patients try many medications in endless combinations and doses and still feel no relief from their depression. Ketamine therapy for depression works quickly, sometimes in just a few hours, to deliver significant relief from symptoms. Most patients enjoy substantial relief within 1-2 days of their 3rd infusion.

Looking for relief from depression? IV Ketamine Infusion Therapy can help.

Ketamine for depression can also deliver relief without any of the negative side effects of other antidepressants, which can include loss of libido, weight gain, insomnia or sleepiness, nausea, dizziness, fatigue, dry mouth, blurred vision, and suicidal ideation.

More and more commonly, patients are starting ketamine treatment earlier in their treatment journey to save time, money, and suffering that stem from less effective treatment options. What was once labeled as a “last resort” by conservative doctors due to its novelty is now a first-line treatment in the fight against the nation’s leading cause of disability – depression.

Seeking Alternative Treatments for Depression?

We speak with many individuals who are looking for alternative treatments for depression because they wish to avoid the side effects of conventional treatments and achieve rapid relief or simply because they have not responded to other treatments. Some patients have tried almost everything; psychotherapy, countless medications, transcranial magnetic stimulation (TMS) and electroconvulsive therapy (ECT.) Even for these patients who have “tried everything” and been labeled as treatment-resistant, IV Ketamine Infusion Therapy often provides substantial relief quickly. Although most of our patients fit this description, we also treat patients who wish to start ketamine therapy much earlier in their treatment journey or who have seen some benefit from other treatments but are moving away from those options due to the reasons listed above.

Is Ketamine Right For Me?

Ketamine treatment for depression

Ketamine Treatments for Depression: How it Works

We administer ketamine treatments for depression through an intravenous infusion of ketamine, which is the most effective route of administration (ROA) and only one that has been scientifically proven to work. A full course of therapy consists of a series of 6 infusions provided over 2-3 weeks with each treatment session lasting 50-55 minutes.

When you undergo ketamine therapy for depression, you’re closely monitored by our highly experienced medical team, led by Dr. Steven L. Mandel. Dr. Mandel is a board-certified anesthesiologist with a master’s degree in psychology and over 35 years of experience administering ketamine. He is a world-renowned pioneer in the administration of ketamine for mood disorders and pain conditions and you can learn more about his credentials here and see media coverage on him here. At Ketamine Clinics LA, we use hospital-grade equipment to monitor your pulse, oxygen saturation, blood pressure, respiratory rate, and electrocardiogram. Even though ketamine is incredibly safe, especially in low doses, we take extra precautions to ensure your safety. You’ll be made comfortable in our spa-like environment where the patient experience is our top priority.

Is Ketamine Safe and Effective?

Yes. Ketamine is recognized as one of the safest, most widely used anesthetics in the world. It’s approved for several medical uses in human and veterinary medicine and is commonly used with young children.

World-renowned institutions have confirmed the efficacy of ketamine infusions for the treatment of mood disorders and various pain conditions. Yale University, Stanford University, Harvard University, UCLA, USC, NYU, the National Institute of Mental Health, the Black Dog Institute of Australia, Cleveland Clinic, and Mt. Sinai Hospital are a few of the leaders.

At Ketamine Clinics of Los Angeles, we offer the best possible chance of relief in our state-of-the-art facility in the Culver City area of Los Angeles, California. Our highly experienced and compassionate team consists of accomplished individuals who have education, training, and experience serving those with mood disorders and chronic pain conditions. Everyone on the KCLA team also has a personal interest and connection to the work we do. Dr. Steven Mandel is a pioneer in this field who has personally administered more ketamine infusions than almost all other providers in the United States.

Depression treatment los angeles

Is Ketamine Therapy Covered by Insurance?

Many insurers will partially reimburse your cost for ketamine treatment for depression. We do not bill insurance, however, we can provide you with billing statements with the necessary CPT codes for you to file a claim.

What Researchers Say About Ketamine

Since 2004, researchers at leading medical institutions have completed over 50 studies proving ketamine’s ability to significantly relieve depressive symptoms. According to The Washington Post, many experts, such as Thomas Insel (former Director of the National Institute of Mental Health), are calling ketamine “the most significant advancement in mental health in 50 years.”

Ketamine Clinics Los Angeles: The Trusted Authority Among Ketamine Clinic Depression Centers

At Ketamine Clinics Los Angeles, we’re proud to have earned recognition as the gold-standard among ketamine clinics for depression. As a AAAASF certified facility, we ensure the most rigorous operating procedures for your health and wellness. With more experience than just about any other clinic, we tailor-fit treatment plans to your needs and work closely with you and your care team from the moment you contact us to long after your initial series. The environment we maintain and the protocols we’ve pioneered ensure your best chance of rapid relief and sustained recovery from the affliction of depression.

Find Hope with Ketamine Therapy for Depression

As the leading provider of ketamine depression treatment centers, we know your best chance of relief is here and we look forward to the opportunity to serve you. Depression can seriously affect your professional life, your personal life, and the people you love most. You owe it to yourself and to them to find an effective depression treatment. Fill out our online contact form or call us at 310-270-0625 today to see if ketamine therapy is right for you.


Mother of PTSD and depression patient

I saw my son once again.

Although all the medical treatment Matt has received was valuable in some way, the only time in 16 years I saw the person who is my son once again quietly emerge, was after the ketamine infusions.

Allen C. 34 year old Male, Engineer

My successes have been phenomenal.

I have cut down on my Effexor to 75 Mg per day. I have eliminated lithium from my regiment and haven’t needed ambien for about month now to sleep. My klonopin I’ve reduced to once every other day. The infusions really helped my depression and chronic pain in my neck. My depression has never been better and I am cutting down on my other medications with great success. Thank you, thank you Dr. Mandel!

37 Year Old Woman, Registered Nurse

When I found Ketamine Clinics of Los Angeles,

When I found Ketamine Clinics of Los Angeles, and began to research the treatment, I felt my spirits lift. I felt hope. From the moment I called their office, I knew I was in good hands. As someone who works in healthcare, I couldn’t believe how kind and attentive Dr. Mandel and his entire staff were. I know they really care about me.

Keith W. 60 year old male, Lawyer

My doctor recommended that I try Ketamine

My doctor recommended that I try Ketamine at this time because he considers that there is now enough clinical information to make an informed decision about its effectiveness and side effects, and specifically recommended Dr. Mandel, who even with a glowing recommendation from someone for whom I have tremendous respect vastly exceeded all of my expectations.


Dr. Mandel has truly made my unlivable life, livable again.

Dr. Mandel has truly made my unlivable life, livable again. My ability to get out of bed early and or nearly right as I wake up has significantly improved. I’m able to keep up with my incredibly hectic schedule. My overall mood is high and lethargy is low. My social anxiety is at an all time low, and I haven’t had a panic attack since my first infusion.

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