PTSD Treatment

Revolutionizing Mental Health Treatment:

Discover New Hope with Innovative PTSD Treatments in Los Angeles, CA

Welcome to Ketamine Clinics Los Angeles, where cutting-edge solutions meet compassionate care. Our clinic stands at the forefront of innovative treatment options, employing a comprehensive approach to transform the lives of our patients.

Ketamine Clinics patient laying in the sun after ketamine for PTSD in Los Angeles

The Science of Ketamine Treatment for PTSD

Ketamine is an NMDA receptor antagonist and an AMPA receptor stimulator. AMPA stimulation is necessary for increasing brain-derived neurotrophic factor (BDNF), which, in turn, stimulates the formation of new receptors and synapses. This process is critical for making connections between neurons and is often severely compromised among those with PTSD, depression, and other mood disorders.

Over 25,000 treatments provided since 2014

Ketamine Clinics Los Angeles, one of the leading mental health treatment centers in the US, provides an innovative mood disorder therapy known as Ketamine Infusion Therapy. Ketamine Clinics LA is committed to providing exceptional care by treating the patient with an effective blend of science, compassion, and humor. To put it simply, Dr. Mandel’s methodology has resulted in the most prestigious and professional ketamine treatment Los Angeles has ever seen.

We offer relief and hope to those who suffer from treatment-resistant conditions. It is our top priority to create a calm, comfortable, and safe environment for every individual. Since opening the doors to our ketamine infusion centers in 2014, we’ve administered over 25,000 treatments!

ketamine for depression treatment Los Angeles

Patient Testimonials

It’s hard to put into words how deeply grateful I am for @ketamineclinicsla. Ketamine therapy is a medical treatment where low doses of ketamine are given through an IV to help with depression, anxiety, PTSD, and chronic pain—especially when nothing else has worked.

It works by calming overactive parts of the brain and helping it build new, healthier connections. The result? A noticeable shift in mood and mental clarity—often faster than traditional treatments.

For the past 4+ years, since Frankie passed so suddenly—followed by losing both of my parents and, most recently, our sweet dog Leonardo—I’ve been navigating deep grief, depression, anxiety, and PTSD. I’ve tried it all: medication, EMDR, talk therapy, Reiki, acupuncture, spiritual healing… you name it. But nothing has come close to the breakthroughs I’ve experienced through ketamine therapy.

This month-long journey hasn’t been easy—it’s been raw, emotional, and intense. But it’s also been profoundly healing. It takes you deep into yourself—your fears, your pain, your truth. It helps you understand what you’ve been carrying, what needs attention, and what you’re finally ready to release.

It’s not a magic cure, but it’s helped my brain begin to heal, to accept, and to allow emotions to move through me instead of burying them. I can finally carry my story with less shame and more compassion.

Endless thanks to Victoria, my practitioner (and now, my friend), for her warmth, love, and support—especially when I wanted to give up.

The biggest lesson? In the end, your greatest healer is always yourself.
God bless.
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Ernesto A.
3/27/2025
The Ketamine Clinics Los Angeles has been a truly life-changing experience. From my first session to the last, I felt supported, understood, and genuinely cared for. Jeffrey and Victoria went above and beyond, providing exceptional care, compassion, and professionalism every step of the way. They made the entire process smooth and reassuring, ensuring I was comfortable and well-informed throughout. Now that I’ve completed all six sessions, I’m incredibly pleased with both the results and the overall experience. I’m deeply grateful for their dedication and highly recommend this clinic to anyone considering ketamine therapy.
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Vika C.
2/24/2025
I can honestly say that ketamine treatment at Ketamine Clinic LA has changed my life in ways I never thought possible. After years of struggling and relying on SSRIs and stimulants just to get through the day, I finally found something that truly works. For the first time in so long, I feel like myself again. What makes this place even more special is the people. The staff here treats you like family—like they’re caring for their own. Every doctor, every nurse, every follow-up feels deeply personal, like they genuinely want to see you heal and thrive. I’ve never felt so seen, so supported, or so hopeful about my future.
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Miriam T.
2/19/2025
I went into my 6 session series of Ketamine treatments at Ketamine Clinics Los Angeles (KCLA) as a therapist wanting to learn more about the ketamine therapy experience in hope of eventually providing supportive services in other people's integration of their ketamine journeys. I couldn't have picked a better place to learn the ropes! The offices and treatment rooms at KCLA are beautiful and modern, yet are still inviting and comfortable, offering a safe environment for my experience from beginning to end. I felt thoroughly supported, respected and attended to by the friendly and knowledgable staff. Even when my first treatment was a little bit difficult, I felt safe to describe what was happening for me and to ask for extra care. At every turn, I was met with an understanding, compassionate and competent response. The nurses and nurse practitioners that I worked with, and even the doctors whom I met, were more than forthcoming about the ketamine therapy process and answered all of my questions and observations with down-to-earth, in-depth information and good humored perspectives. I would highly recommend KCLA as a therapeutic home for anyone looking for support on their healing path!
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Melissa S.
2/05/2025
Incredible! They changed my life. I was dealing with really bad depression starting in Jan 2020 and tried all of the things. Eventually I had a doctor recommend Ketamine therapy and went to the Ketamine Clinics Los Angeles purely based on their Google reviews (5 stars). This was in Fall of 2021. I had 6 sessions of ketamine intravenously administered over the course of 3 weeks. The staff and nurses are so wonderful here - everyone was so sweet and kind and made me feel like things were going to be okay. I had a lot of anxiety since I'd never done anything like this before but they were wonderful. They check on you during the 50 minutes, and really go above and beyond. It took 2 weeks after my last appointment to start really feeling better in a way I hadn't in so long. I could go on and on but ultimately it really changed my life. I did return in Spring of 2023 for 2 sessions since I felt myself starting to slip back into depression. The 2 sessions did the trick and it's now January 2025 and I feel wonderful. Life still happens and can be so rough but now I feel like I have the mental endurance to get through it. I highly recommend! Also - don't let news stories of people who use drugs recreationally or irresponsibly dissuade you from trying ketamine therapy if you are depressed. This is completely different and everyone at this clinic is highly trained. Safety and helping people is their top priority.
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Sophie H.
2/05/2025
My experience has been wonderful at KCLA. Everyone is very courteous and the nurses are so caring and friendly. The facility is clean and the treatment is controlled, and I felt completely safe. I am happy (literally) to recommend Ketamine Clinics Los Angeles.
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lisa c.
12/18/2024

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