Welcome to Ketamine Clinics Los Angeles (KCLA)

World-renowned pioneers of Ketamine Infusion Therapy for mental health.
A leading provider of evidence-based, comprehensive mental health care.

Ketamine Clinics Los Angeles (KCLA) is a world-renowned ketamine clinic specializing in intravenous (IV) infusions of ketamine for various mental health conditions such as depression, anxiety, PTSD, suicidality, and other mood disorders. Co-founded by Dr. Steven L. Mandel and CEO Sam Mandel in 2014, KCLA emerged as one of the pioneering ketamine clinics in the United States. With a strong focus on advancing mental health treatment, the Mandels have been at the forefront of utilizing ketamine therapy, delivering more than 30,000 infusions with a notable 83% success rate over 10 years. KCLA takes pride in being the first and only ketamine clinic accredited by Quad A, upholding the gold standard in safety, efficacy, and patient satisfaction.

With a commitment to holistic care, KCLA has recently expanded its services to include Psychiatric Medication Management and Transcranial Magnetic Stimulation (TMS), with plans for further advancements in the near future. They are excited about the healing potential of other psychedelics like MDMA and psilocybin, aiming to integrate these medicines and others into the practice when they become legally available. KCLA has contracted with ten of California’s largest health insurance plans to expand access to their services.

Your care team at KCLA comprises an exceptional group of highly skilled professionals regarded as leaders in their field. The team includes an Anesthesiologist with a master’s degree in Psychology, Psychiatrists, Psychiatric Mental Health Nurse Practitioners (PMHNPs), Registered Nurses, and Administrative support staff. All teammates collaborate in person at KCLA’s state-of-the-art, 5,000-square-foot facility in Los Angeles, CA.

KCLA Care Team

The clinical team at KCLA comprises an exceptional group of highly skilled professionals regarded as leaders in their field. The team includes one Anesthesiologist with a master’s degree in psychology, two Psychiatrists (double and triple-board-certified), one Physician Assistant, one Psychiatric Mental Health Nurse Practitioner, four Registered Nurses, and six administrative staff. All teammates collaborate in KCLA’s state-of-the-art, 5,000-square-foot healing center in Los Angeles, CA.

What is Ketamine Infusion Therapy?

Ketamine Infusion Therapy is a clinically-proven, safe, and effective treatment for mental health conditions. Treatment consists of the gradual, intravenous infusion of the medicine ketamine, an anesthetic approved by the FDA in 1970. When used to treat mood disorders, a much lower dose of ketamine is administered so patients are conscious and awake the entire time. Every clinic has different protocols. At KCLA, patients receive a series of six 55-minute infusions over 2-3 weeks in a state-of-the-art facility staffed with world-class experts. Each patient receives a private room and is monitored the entire time, ensuring a safe and comfortable experience. Many patients experience significant relief from symptoms after just one infusion. However, the majority require at least three infusions before improvement, and others only benefit after completing the entire series of six, sometimes weeks later. It’s crucial to complete the whole series for maximum effect and duration of relief. KCLA has a leading success rate of 83%, even for treatment-resistant cases, and no long-term side effects.


Zero long-term side effects


Results usually seen in 4 days


83% success rate


10 years of world-class care


6,000+ patients served


25,000+ infusions provided

Conditions Treated

Ketamine Clinics Los Angeles specializes in treating various mental health conditions with evidence-based solutions. Dedicated to identifying each patient’s unique needs and matching them with the proper treatment, patients enjoy better outcomes more quickly so they can thrive.

Ketamine Infusion Therapy

At KCLA, patients infuse in a private room with hospital-grade monitoring equipment and continuous monitoring by the medical team. They are made comfortable in premium reclining chairs with pillows, blankets, sleep masks, noise-canceling headphones, and an unlimited selection of relaxing music. 

The experienced and compassionate medical team is dedicated to patient safety and comfort, with a reputation for anticipating patients’ needs before they arise. The entire team at KCLA is committed to nurturing patients on their path from cope to HOPE. 

Psychiatric Medication Management

Double-board-certified psychiatrist Dr. Peyman Tashkandi and triple-board-certified psychiatrist Dr. Suzanne Dupee lead KCLA’s medication management program. These physicians and advanced practice providers working with them are holistic clinicians passionate about treating the whole person with compassion and the full range of psychiatric medications available today. Their focus is identifying the minimum effective dose and number of medications necessary to meet each patient’s goals while minimizing side effects. KCLA now accepts nine of California’s largest health insurance plans for medication management and offers both in-person and virtual visits.  

TMS therapy for depression in Los Angeles

Transcranial Magnetic Stimulation (TMS)

Transcranial Magnetic Stimulation (TMS) is a non-invasive, effective, FDA-approved treatment for depression and obsessive-compulsive disorder (OCD) that uses magnetic fields to stimulate nerve cells in the brain. TMS relieves symptoms approximately 70% of the time and generally requires at least 2-3 weeks of treatment before any improvement. TMS treatments can be as short as three minutes or as long as 25 minutes, with appointments typically lasting 20-60 minutes. 

Treatment is provided in KCLA’s luxurious, private treatment rooms equipped with Samsung Frame smart TVs with high-resolution art displays, entertainment, and more. TMS is generally well-tolerated, with few short-term side effects. TMS may be a suitable option for patients who have not responded to other treatments, such as prescription medication or talk therapy, or who cannot tolerate the side effects of these treatments. KCLA now accepts nine of California’s largest health insurance plans for TMS.    

KCLA Accepts Most Health Insurance Plans

Ketamine Infusion Therapy remains a non-covered, cash-pay service.

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KCLA Accepts Most Health Insurance Plans

Four Simple Steps to Relief

Schedule your free phone consultation.

Confirm your eligibility with your Provider.

Schedule your appointment with your Provider.

Begin your journey to wellness.

What patients are saying...

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KCLA in the Media

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